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2018-2020年度科研成果

發布時間：2021-05-10 14:12:51 作者：本站編輯來源：本站原創瀏覽次數：

發表科研論文
題目	作者	期刊	發表時間	級別
15-Lipoxygenase/15-hydroxyeicosanoid and activator protein 1 contribute to hypoxia-induced pulmonary artery smooth muscle cells phenotype alteration	Yan Xing, Xiaodong Zheng , Jing Qi , Yao Fu , Weiwei Cao , Jiali Li , Daling Zhu	Prostaglandins Leukot Essent Fatty Acids	2018.08	SCI
5-BDBD ameliorates an OVA-induced allergic asthma by the reduction of Th2 cytokines production	Bing Hu , Xiaoqian Feng , Li Wang , Yinli Song , Xiuqin Ni	Iran J Basic Med Sci	2018.04	SCI
Activation of transient receptor potential vanilloid 3 channel (TRPV3) aggravated pathological cardiac hypertrophy via calcineurin/NFATc3 pathway in rats	Qianhui Zhang, Hanping Qi , Yonggang Cao , Pilong Shi , Chao Song , Lina Ba , Yunping Chen , Jingquan Gao , Shuzhi Li , Baiyan Li , Hongli Sun	J Cell Mol Med	2018.12	SCI
Allicin improves the function of cardiac microvascular endothelial cells by increasing PECAM-1 in rats with cardiac hypertrophy	Pilong Shi , Yonggang Cao , Jingquan Gao , Bowen Fu , Jing Ren , Lina Ba , Chao Song , Hanping Qi , Wei Huang , Xueying Guan , Hongli Sun	Phytomedicine	2018.12	SCI
The transient receptor potential vanilloid-3 regulates hypoxia-mediated pulmonary artery smooth muscle cells proliferation via PI3K/AKT signaling pathway	Qianlong Zhang , Yonggang Cao , Qian Luo , Peng Wang , Pilong Shi , Chao Song , Mingyao E , Jing Ren , Bowen Fu , Hongli Sun	Cell Prolif	2018.06	SCI
Transient receptor potential vanilloid-3 (TRPV3) activation plays a central role in cardiac fibrosis induced by pressure overload in rats via TGF-β1 pathway	Yan Liu , Hanping Qi , Mingyao E , Pilong Shi , Qianhui Zhang , Shuzhi Li , Ye Wang , Yonggang Cao , Yunping Chen , Lina Ba , Jingquan Gao , Wei Huang , Hongli Sun	Naunyn Schmiedebergs Arch Pharmacol	2018.02	SCI
P2X4R promotes airway remodeling by acting on the phenotype switching of bronchial smooth muscle cells in rats	Li Wang , Xiaoqian Feng , Bing Hu , Qingqing Xia , Xiuqin Ni , Yinli Song	Purinergic Signal	2018.12	SCI
15-Lipoxygenase-2/15(S)-hydroxyeicosatetraenoic acid regulates cell proliferation and metastasis via the STAT3 pathway in lung adenocarcinoma	Lin Yang , Cui Ma , Lixin Zhang , Min Zhang , Fei Li , Chen Zhang , Xiufeng Yu , Xiaoying Wang , Siyu He , Daling Zhu , Yinli Song	Prostaglandins Other Lipid Mediat	2018.09	SCI
alpha1A-adrenoceptor is involved in norepinephrine-induced proliferation of pulmonary artery smooth muscle cells via CaMKII signaling.	Qian Luo , Xiaoyan Wang , Ruxia Liu , Hui Qiao , Peng Wang , Chao Jiang , Qianlong Zhang , Yonggang Cao , Hang Yu , Lihui Qu	J Cell Biochem	2019.06	SCI
Potential Role of Cartilage Oligomeric 1 Matrix Protein in the Modulation of Pulmonary Arterial Smooth Muscle Superoxide by Hypoxia	Hang Yu , Norah Alruwaili , Bing Hu , Melissa R Kelly , Bin Zhang , Dong Sun , Michael S Wolin	Am J Physiol Lung Cell Mol Physiol	2019.11	SCI
Deletion of Neuropeptide Y Attenuates Cardiac Dysfunction and Apoptosis During Acute Myocardial Infarction	Wei Huang , Qianhui Zhang , Hanping Qi , Pilong Shi , Chao Song , Yongsheng Liu , Hongli Sun	Front Pharmacol	2019.10	SCI
Long Noncoding RNA-Maternally Expressed Gene 3 Contributes to Hypoxic Pulmonary Hypertension	Yan Xing , Xiaodong Zheng , Yao Fu , Jing Qi , Minghui Li , Mingfei Ma , Shuang Wang , Shuzhen Li , Daling Zhu	Mol Ther	2019.12	SCI
The neuroprotective e?ects of carvacrol on ischemia/reperfusion-induced hippocampal neuronal impairment by ferroptosis mitigation	Xueying Guan , Xiaolei Li , Xuejiao Yang , Junwei Yan , Pilong Shi , Lina Ba , Yonggang Cao , Peng Wang	Life Sci.	2019.10	SCI
Resveratrol inhibits lipid accumulation in the intestine of atherosclerotic mice and macrophages.	Guozhu Ye, Guoyou Chen, Han Gao, Yi Lin , Xu Liao, Han Zhang , Xinyu Liu , Yulang Chi , Qiansheng Huang , Huimin Zhu , Yuhua Fan , Sijun Dong	J Cell Mol Med .	2019.06	SCI
mi R -15a/15b Cluster Modulates Survival of Mesenchymal Stem Cells to Improve Its Therapeutic Efficacy of Myocardial Infarction.	Yingfeng Tu, Yan Qiu , Li Liu , Tao Huang , Hao Tang , Youbin Liu , Wenguang Guo , Hongchi Jiang , Yuhua Fan , Bo Yu	J Am Heart Assoc .	2019.01	SCI
MiR-103 inhibiting cardiac hypertrophy through inactivation of myocardial cell autophagy via targeting TRPV3 channel in rat hearts.	Hanping Qi , Jing Ren , Mingyao E , Qianhui Zhang , Yonggang Cao , Lina Ba , Chao Song , Pilong Shi , Bowen Fu , Hongli Sun	J Cell Mol Med .	2019.03	SCI
Allicin attenuates pathological cardiac hypertrophy by inhibiting autophagy via activation of PI3K/Akt/mTOR and MAPK/ERK/mTOR signaling pathways.	Lina Ba , Jingquan Gao , Yunping Chen , Hanping Qi , Chonghui Dong , Hao Pan , Qianhui Zhang , Pilong Shi , Chao Song , Xueying Guan , Yonggang Cao , Hongli Sun	Phytomedicine .	2019.05	SCI
Potential Role of Cartilage Oligomeric 1 Matrix Protein in the Modulation of Pulmonary Arterial Smooth Muscle Superoxide by Hypoxia	Hang Yu , Norah Alruwaili , Bing Hu 1, Melissa R Kelly , Bin Zhang , Dong Sun , Michael S Wolin	Am J Physiol Lung Cell Mol Physiol .	2019.11	SCI
alpha1A-adrenoceptor is involved in norepinephrine-induced proliferation of pulmonary artery smooth muscle cells via CaMKII signaling	Qian Luo , Xiaoyan Wang , Ruxia Liu , Hui Qiao , Peng Wang , Chao Jiang , Qianlong Zhang , Yonggang Cao , Hang Yu 1, Lihui Qu	J Cell Biochem .	2019.06	SCI
Deletion of Neuropeptide Y Attenuates Cardiac Dysfunction and Apoptosis During Acute Myocardial Infarction	Wei Huang , Qianhui Zhang , Hanping Qi, Pilong Shi , Chao Song , Yongsheng Liu , Hongli Sun	Front Pharmacol .	2019.10	SCI
Novel lncRNA PSMG3?AS1 functions as a miR?143?3p sponge to increase the proliferation and migration of breast cancer cells	Yue Cui , Yuhua Fan , Guangcai Zhao , Qibing Zhang , Ying Bao , Yuanri Cui , Zengjie Ye , Guoyou Chen , Xianji Piao, Fang Guo , Jinghao Wang , Yuhua Bai , Dejun Yu	Oncol Rep.	2020.01	SCI
Electrical stimulation inhibits Val-boroPro-induced pyroptosis in THP-1 macrophages via sirtuin3 activation to promote autophagy and inhibit ROS generation	Lin Cong , Ziyu Gao , Yinghong Zheng , Ting Ye , Zitong Wang , Pengyu Wang , Manman Li , Bowen Dong , Wei Yang , Quanfeng Li , Shupei Qiao , Cao Wang , Yijun Shen , Hong Li , Weiming Tian , Liming Yang	Aging (Albany NY) .	2020.04	SCI
Estradiol-Induced MMP-9 Expression via PELP1-Mediated Membrane-Initiated Signaling in ERα-Positive Breast Cancer Cells	Yu Pan , Xiuli Wang , Yanzhi Zhang , Juanjuan Qiao , Hironobu Sasano , Keely McNamara , Baoshan Zhao , Dongmei Zhang , Yuhua Fan , Lili Liu , Xueling Jia , Ming Liu , Sihang Song , Lin Wang	Horm Cancer .	2020.04	SCI
MSTN Attenuates Cardiac Hypertrophy through Inhibition of Excessive Cardiac Autophagy by Blocking AMPK /mTOR and miR-128/PPARγ/NF-κB	Hanping Qi , Jing Ren , Lina Ba, Chao Song , Qianhui Zhang , Yonggang Cao , Pilong Shi , Bowen Fu , Yongsheng Liu , Hongli Sun	Mol Ther Nucleic Acids .	2020.03	SCI
The Vascular Dilatation Induced by Hydroxysafflor yellow A (HSYA) on Rat Mesenteric Artery Through TRPV4-dependent Calcium Influx in Endothelial Cell	Jianfeng Yang , Rui Wang , Xiaohan Cheng , HuiChong Qu , Jing Qi , Dan Li , Yan Xing , Yuhua Bai , Xiaodong Zheng	J Ethnopharmacol .	2020.06	SCI
Chemical constituents from the fruits of Piper longum L. and their vascular relaxation effect on rat mesenteric arteries	Dan Li , Rui Wang , Xiaohan Cheng , Jianfeng Yang , Yihui Yang , Huichong Qu , Sen Li , Shan Lin , Donghua Wei , Yuhua Bai , Xiaodong Zheng	Nat Prod Res .	2020.08	SCI
Inhibition of lncRNA Gm15834 attenuates autophagy-mediated myocardial hypertrophy via miR-30b-3p/ULK1 axis in mice	Chao Song , Hanping Qi , Yongsheng Liu , Yunping Chen , Pilong Shi , Shu Zhang , Jing Ren , Lixin Wang , Yonggang Cao , Hongli Sun	Mol Ther .	2021.03	SCI

學術成果獎
成果名稱	完成人	獎勵名稱
Galectin-3調節肺動脈高壓大鼠血管外膜滋養血管形成中的網絡機制	王曉艷	大慶市科技進步獎
法醫學社會服務與科學研究一體化平臺建設	王麟	大慶市科技進步獎
藥物介導的生物醫學工程治療動脈粥樣硬化作用和機制探究	楊力明	黑龍江省醫藥衛生科學技術獎

科研立項
課題編號	立項名稱	主持人	項目來源	執行年限	資助金額（萬元）
81872856	心肌肥厚發生的新機制—lncRNA Gm15834/miR-30b/ULK1/自噬調控網絡參與心肌肥厚的作用及機制	孫宏麗	國家自然科學基金	2019.01-2023.12	57
2018M630378	MSTN通過miR-30e 和 AMPK/mTOR通路對心肌肥厚的作用研究	戚漢平	中國博士后科學基金項目	2018.09-2021.09	8
LH2019H009	剪切力對非小細胞肺癌細胞增殖和遷移影響的機制研究	曹永剛	黑龍江省自然科學基金	2019.7-2022.7	10
2019M661297	血管平滑肌收縮新機制：鈣離子、細胞自噬誘導血管收縮	張彥秋	中國博士后科學基金項目	2019.10-2022.10	8
	血管疾病新細胞分子靶點、模式動物和轉化醫學研究	鄭曉東	中央支持地方高校發展基金-優秀青年人才支持計劃	2019.12-2022.11	100
81973313	lncRNA GAS5介導DNA甲基化在動脈粥樣硬化中誘導巨噬細胞焦亡作用及機制研究	范玉華	國家自然科學基金	2020.1-2023.12	55
LH2020H031	PELP1調控GSDME焦亡參與乳腺癌對紫杉醇耐藥的機制研究	王麟	黑龍江省自然科學基金	2020.7-2023.7	10
LH2020H027	環狀RNA-Tnnc2通過調控自噬參與肺動脈平滑肌細胞增殖	曲麗輝	黑龍江省自然科學基金	2020.7-2023.7	10
91939104	聯合OCT基于Galectin-3為靶點的褪黑素促TFEB去乙?；T導巨噬細胞自噬穩定動脈粥樣硬化易損斑塊的機制研究	楊力明	國家自然科學基金重大研究計劃培育項目	2020.01-2021.12	45

2018-2020年，基礎醫學院共發表SCI文章28篇，單篇最高影響因子8.986。共獲國家自然科學基金3項，中央支持地方高校發展基金-優秀青年人才支持計劃1項，黑龍江省自然科學基金面上資助3項，中國博士后科學基金項目2項，累計科研經費303萬。

上一篇：2014-2017年度科研成果下一篇：2020-2021年度科研成果