您好,歡迎光臨哈爾濱醫科大學(大慶)! 返回首頁聯系我們

                    科學研究 當前位置:首頁 - 學術科研 - 科學研究

                    2018-2020年度科研成果

                    發布時間:2021-05-10 14:12:51  作者:本站編輯  來源:本站原創  瀏覽次數:

                    發表科研論文

                    題目

                    作者

                    期刊

                    發表時間

                    級別

                    15-Lipoxygenase/15-hydroxyeicosanoid   and activator protein 1 contribute to hypoxia-induced pulmonary artery smooth   muscle cells phenotype alteration

                    Yan Xing,   Xiaodong Zheng , Jing Qi , Yao Fu , Weiwei Cao , Jiali Li , Daling Zhu

                    Prostaglandins   Leukot Essent Fatty Acids

                     

                    2018.08

                    SCI

                    5-BDBD   ameliorates an OVA-induced allergic asthma by the reduction of Th2 cytokines   production

                    Bing Hu ,   Xiaoqian Feng , Li Wang , Yinli Song , Xiuqin Ni

                    Iran J Basic Med   Sci

                     

                    2018.04

                    SCI

                    Activation of   transient receptor potential vanilloid 3 channel (TRPV3) aggravated   pathological cardiac hypertrophy via calcineurin/NFATc3 pathway in rats

                    Qianhui Zhang,   Hanping Qi , Yonggang Cao , Pilong Shi , Chao Song , Lina Ba , Yunping Chen ,   Jingquan Gao , Shuzhi Li , Baiyan Li , Hongli Sun

                    J Cell Mol Med

                    2018.12

                    SCI

                    Allicin improves the function of cardiac microvascular endothelial cells   by increasing PECAM-1 in rats with cardiac hypertrophy

                    Pilong Shi ,   Yonggang Cao , Jingquan Gao , Bowen Fu , Jing Ren , Lina Ba , Chao Song ,   Hanping Qi , Wei Huang , Xueying Guan , Hongli Sun

                    Phytomedicine

                     

                    2018.12

                    SCI

                    The transient receptor potential vanilloid-3 regulates hypoxia-mediated pulmonary   artery smooth muscle cells proliferation via PI3K/AKT signaling pathway

                    Qianlong Zhang ,   Yonggang Cao , Qian Luo , Peng Wang , Pilong Shi , Chao Song , Mingyao E ,   Jing Ren , Bowen Fu , Hongli Sun

                    Cell Prolif

                     

                    2018.06

                    SCI

                    Transient receptor potential vanilloid-3 (TRPV3) activation plays a   central role in cardiac fibrosis induced by pressure overload in rats via   TGF-β1 pathway

                    Yan Liu ,   Hanping Qi , Mingyao E , Pilong Shi , Qianhui Zhang , Shuzhi Li , Ye Wang ,   Yonggang Cao , Yunping Chen , Lina Ba , Jingquan Gao , Wei Huang , Hongli Sun  

                    Naunyn   Schmiedebergs Arch Pharmacol

                     

                    2018.02

                    SCI

                    P2X4R promotes airway remodeling by acting on the phenotype switching of   bronchial smooth muscle cells in rats

                    Li Wang ,   Xiaoqian Feng , Bing Hu , Qingqing Xia , Xiuqin Ni , Yinli Song

                    Purinergic   Signal

                    2018.12

                    SCI

                    15-Lipoxygenase-2/15(S)-hydroxyeicosatetraenoic acid regulates cell   proliferation and metastasis via the STAT3 pathway in lung adenocarcinoma

                    Lin Yang , Cui   Ma , Lixin Zhang , Min Zhang , Fei Li , Chen Zhang , Xiufeng Yu , Xiaoying   Wang , Siyu He , Daling Zhu , Yinli Song

                    Prostaglandins   Other Lipid Mediat

                     

                    2018.09

                    SCI

                    alpha1A-adrenoceptor is involved in norepinephrine-induced proliferation   of pulmonary artery smooth muscle cells via CaMKII signaling.

                    Qian Luo ,   Xiaoyan Wang , Ruxia Liu , Hui Qiao , Peng Wang , Chao Jiang , Qianlong Zhang   , Yonggang Cao , Hang Yu , Lihui Qu

                    J Cell Biochem

                     

                    2019.06

                    SCI

                    Potential Role of Cartilage Oligomeric 1 Matrix Protein in the   Modulation of
                      Pulmonary Arterial Smooth Muscle Superoxide by Hypoxia

                    Hang Yu , Norah   Alruwaili , Bing Hu , Melissa R Kelly , Bin Zhang  , Dong Sun , Michael S Wolin

                    Am J Physiol   Lung Cell Mol Physiol

                     

                    2019.11

                    SCI

                    Deletion of Neuropeptide Y
                      Attenuates Cardiac Dysfunction
                      and Apoptosis During Acute
                      Myocardial Infarction

                    Wei Huang ,   Qianhui Zhang , Hanping Qi , Pilong Shi , Chao Song , Yongsheng Liu , Hongli   Sun

                    Front Pharmacol

                     

                    2019.10

                    SCI

                    Long Noncoding RNA-Maternally Expressed Gene 3 Contributes to Hypoxic   Pulmonary Hypertension

                    Yan Xing ,   Xiaodong Zheng , Yao Fu , Jing Qi , Minghui Li , Mingfei Ma , Shuang Wang ,   Shuzhen Li , Daling Zhu

                    Mol Ther

                     

                    2019.12

                    SCI

                    The neuroprotective e?ects of carvacrol on ischemia/reperfusion-induced
                      hippocampal neuronal impairment by ferroptosis mitigation

                    Xueying Guan ,   Xiaolei Li , Xuejiao Yang , Junwei Yan , Pilong Shi , Lina Ba , Yonggang Cao   , Peng Wang

                    Life Sci.

                    2019.10

                    SCI

                    Resveratrol inhibits lipid accumulation in the intestine of   atherosclerotic mice and macrophages.

                    Guozhu Ye,   Guoyou Chen, Han Gao, Yi Lin , Xu Liao, Han Zhang , Xinyu Liu , Yulang Chi ,   Qiansheng Huang , Huimin Zhu , Yuhua Fan , Sijun Dong

                    J Cell Mol Med

                    .

                    2019.06

                    SCI

                    mi R -15a/15b Cluster Modulates Survival of Mesenchymal Stem Cells to   Improve Its Therapeutic Efficacy of Myocardial Infarction.

                    Yingfeng Tu, Yan   Qiu , Li Liu , Tao Huang , Hao Tang , Youbin Liu , Wenguang Guo , Hongchi   Jiang , Yuhua Fan , Bo Yu

                    J Am Heart Assoc

                    .

                    2019.01

                    SCI

                    MiR-103 inhibiting cardiac hypertrophy through inactivation of   myocardial cell autophagy via targeting TRPV3 channel in rat hearts.

                    Hanping Qi ,   Jing Ren , Mingyao E , Qianhui Zhang , Yonggang Cao , Lina Ba , Chao Song ,   Pilong Shi , Bowen Fu , Hongli Sun

                    J Cell Mol Med

                    .

                    2019.03

                    SCI

                    Allicin attenuates pathological cardiac hypertrophy by inhibiting   autophagy via activation of PI3K/Akt/mTOR and MAPK/ERK/mTOR signaling   pathways.

                    Lina Ba ,   Jingquan Gao , Yunping Chen , Hanping Qi , Chonghui Dong , Hao Pan , Qianhui Zhang   , Pilong Shi , Chao Song , Xueying Guan , Yonggang Cao , Hongli Sun

                    Phytomedicine

                    .

                    2019.05

                    SCI

                    Potential Role of Cartilage Oligomeric 1 Matrix Protein in the   Modulation of Pulmonary Arterial Smooth Muscle Superoxide by Hypoxia

                    Hang Yu , Norah Alruwaili   , Bing Hu 1, Melissa R Kelly , Bin Zhang , Dong Sun , Michael S Wolin

                    Am J Physiol   Lung Cell Mol Physiol

                    .

                    2019.11

                    SCI

                    alpha1A-adrenoceptor is involved in norepinephrine-induced proliferation   of pulmonary artery smooth muscle cells via CaMKII signaling

                    Qian Luo ,   Xiaoyan Wang , Ruxia Liu , Hui Qiao , Peng Wang , Chao Jiang , Qianlong Zhang   , Yonggang Cao , Hang Yu 1, Lihui Qu

                    J Cell Biochem

                    .

                    2019.06

                    SCI

                    Deletion of Neuropeptide Y Attenuates Cardiac Dysfunction and Apoptosis   During Acute Myocardial Infarction

                    Wei Huang ,   Qianhui Zhang , Hanping Qi, Pilong Shi , Chao Song , Yongsheng Liu , Hongli   Sun

                    Front Pharmacol

                    .

                    2019.10

                    SCI

                    Novel lncRNA   PSMG3?AS1   functions as a miR?143?3p sponge to increase the proliferation and migration of   breast cancer cells

                    Yue Cui , Yuhua   Fan , Guangcai Zhao , Qibing Zhang , Ying Bao , Yuanri Cui , Zengjie Ye ,   Guoyou Chen , Xianji Piao, Fang Guo , Jinghao Wang , Yuhua Bai , Dejun Yu

                    Oncol Rep.

                    2020.01

                    SCI

                    Electrical   stimulation inhibits Val-boroPro-induced pyroptosis in THP-1 macrophages via   sirtuin3 activation to promote autophagy and inhibit ROS generation

                    Lin Cong , Ziyu   Gao , Yinghong Zheng , Ting Ye , Zitong Wang , Pengyu Wang , Manman Li ,   Bowen Dong , Wei Yang , Quanfeng Li , Shupei Qiao , Cao Wang , Yijun Shen ,   Hong Li , Weiming Tian , Liming Yang

                    Aging (Albany   NY)

                    .

                    2020.04

                    SCI

                    Estradiol-Induced   MMP-9 Expression via PELP1-Mediated Membrane-Initiated Signaling in ERα-Positive   Breast Cancer Cells

                    Yu Pan , Xiuli   Wang , Yanzhi Zhang , Juanjuan Qiao , Hironobu Sasano , Keely McNamara ,   Baoshan Zhao , Dongmei Zhang , Yuhua Fan , Lili Liu , Xueling Jia , Ming Liu   , Sihang Song , Lin Wang

                    Horm Cancer

                    .

                    2020.04

                    SCI

                    MSTN Attenuates Cardiac Hypertrophy through Inhibition of Excessive   Cardiac Autophagy by Blocking AMPK /mTOR and miR-128/PPARγ/NF-κB

                     

                     

                    Hanping Qi ,   Jing Ren , Lina Ba, Chao Song , Qianhui Zhang , Yonggang Cao , Pilong Shi ,   Bowen Fu , Yongsheng Liu , Hongli Sun

                    Mol Ther Nucleic   Acids

                    .

                    2020.03

                    SCI

                    The Vascular   Dilatation Induced by Hydroxysafflor yellow A (HSYA) on Rat Mesenteric Artery   Through TRPV4-dependent Calcium Influx in Endothelial Cell

                    Jianfeng Yang ,   Rui Wang , Xiaohan Cheng , HuiChong Qu , Jing Qi , Dan Li , Yan Xing , Yuhua Bai   , Xiaodong Zheng

                    J Ethnopharmacol

                    .

                    2020.06

                    SCI

                    Chemical   constituents from the fruits of Piper longum L. and their vascular relaxation   effect on rat mesenteric arteries

                    Dan Li , Rui   Wang , Xiaohan Cheng , Jianfeng Yang , Yihui Yang , Huichong Qu , Sen Li ,   Shan Lin , Donghua Wei , Yuhua Bai , Xiaodong Zheng

                    Nat Prod Res

                    .

                    2020.08

                    SCI

                    Inhibition of lncRNA   Gm15834 attenuates autophagy-mediated myocardial hypertrophy via miR-30b-3p/ULK1   axis in mice

                    Chao Song ,   Hanping Qi , Yongsheng Liu , Yunping Chen , Pilong Shi , Shu Zhang , Jing Ren   , Lixin Wang , Yonggang Cao , Hongli Sun

                    Mol Ther

                    .

                    2021.03

                    SCI

                     

                    學術成果獎

                    成果名稱

                    完成人

                    獎勵名稱

                     Galectin-3調節肺動脈高壓大鼠血管外膜滋養血管形成中的網絡機制

                    王曉艷

                    大慶市科技進步獎

                     法醫學社會服務與科學研究一體化平臺建設 

                    王麟

                    大慶市科技進步獎

                     藥物介導的生物醫學工程治療動脈粥樣硬化作用和機制探究 

                    楊力明

                    黑龍江省醫藥衛生科學技術獎


                    科研立項

                    課題編號

                    立項名稱

                    主持人

                    項目來源

                    執行年限

                    資助金額(萬元)

                    81872856

                    心肌肥厚發生的新機制—lncRNA   Gm15834/miR-30b/ULK1/自噬調控網絡參與心肌肥厚的作用及機制

                    孫宏麗

                    國家自然科學基金

                    2019.01-2023.12

                    57

                    2018M630378

                    MSTN通過miR-30e 和 AMPK/mTOR通路對心肌肥厚的作用研究

                    戚漢平

                    中國博士后科學基金項目

                    2018.09-2021.09

                    8

                    LH2019H009

                    剪切力對非小細胞肺癌細胞增殖和遷移影響的機制研究

                    曹永剛

                    黑龍江省自然科學基金

                    2019.7-2022.7

                    10

                    2019M661297

                    血管平滑肌收縮新機制:鈣離子、細胞自噬誘導血管收縮

                    張彥秋

                    中國博士后科學基金項目

                    2019.10-2022.10

                    8


                    血管疾病新細胞分子靶點、模式動物和轉化醫學研究

                    鄭曉東

                    中央支持地方高校發展基金-優秀青年人才支持計劃

                    2019.12-2022.11

                    100

                    81973313

                    lncRNA   GAS5介導DNA甲基化在動脈粥樣硬化中誘導巨噬細胞焦亡作用及機制研究

                    范玉華

                    國家自然科學基金

                    2020.1-2023.12

                    55

                    LH2020H031

                    PELP1調控GSDME焦亡參與乳腺癌對紫杉醇耐藥的機制研究

                    王麟

                    黑龍江省自然科學基金

                    2020.7-2023.7

                    10

                    LH2020H027

                    環狀RNA-Tnnc2通過調控自噬參與肺動脈平滑肌細胞增殖

                    曲麗輝

                    黑龍江省自然科學基金

                    2020.7-2023.7

                    10

                    91939104

                    聯合OCT基于Galectin-3為靶點的褪黑素促TFEB去乙?;T導巨噬細胞自噬穩定動脈粥樣硬化易損斑塊的機制研究

                    楊力明

                    國家自然科學基金重大研究計劃培育項目

                    2020.01-2021.12

                    45

                     

                            2018-2020年,基礎醫學院共發表SCI文章28篇,單篇最高影響因子8.986。共獲國家自然科學基金3項,中央支持地方高校發展基金-優秀青年人才支持計劃1項,黑龍江省自然科學基金面上資助3項,中國博士后科學基金項目2項,累計科研經費303萬。

                    地址:黑龍江省大慶市高新區新陽路 39 郵政編碼:163319
                    版權所有:哈爾濱醫科大學大慶校區
                    黑ICP備2021002235號-1
                    版權所有:哈爾濱醫科大學大慶校區
                    地址:黑龍江省大慶市高新區新陽路39
                    黑ICP備2021002235號-1
                    久久久久久亚洲Av片无码